http://purl.uniprot.org/citations/17662947 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17662947 | http://www.w3.org/2000/01/rdf-schema#comment | "Nutrient availability is one of the strongest determinants of cell size. When grown in rich media, single-celled organisms such as yeast and bacteria can be up to twice the size of their slow-growing counterparts. The ability to modulate size in a nutrient-dependent manner requires cells to: (1) detect when they have reached the appropriate mass for a given growth rate and (2) transmit this information to the division apparatus. We report the identification of a metabolic sensor that couples nutritional availability to division in Bacillus subtilis. A key component of this sensor is an effector, UgtP, which localizes to the division site in a nutrient-dependent manner and inhibits assembly of the tubulin-like cell division protein FtsZ. This sensor serves to maintain a constant ratio of FtsZ rings to cell length regardless of growth rate and ensures that cells reach the appropriate mass and complete chromosome segregation prior to cytokinesis."xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2007.05.043"xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/author | "Lee A.H."xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/author | "Weart R.B."xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/author | "Levin P.A."xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/author | "Chien A.C."xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/author | "Hill N.S."xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/author | "Haeusser D.P."xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/pages | "335-347"xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/title | "A metabolic sensor governing cell size in bacteria."xsd:string |
http://purl.uniprot.org/citations/17662947 | http://purl.uniprot.org/core/volume | "130"xsd:string |
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http://purl.uniprot.org/citations/17662947 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17662947 |
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