http://purl.uniprot.org/citations/17668382 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17668382 | http://www.w3.org/2000/01/rdf-schema#comment | "Type 2 diabetes (T2D) is a common, polygenic chronic disease with high heritability. The purpose of this whole-genome association study was to discover novel T2D-associated genes. We genotyped 500 familial cases and 497 controls with >300,000 HapMap-derived tagging single-nucleotide-polymorphism (SNP) markers. When a stringent statistical correction for multiple testing was used, the only significant SNP was at TCF7L2, which has already been discovered and confirmed as a T2D-susceptibility gene. For a replication study, we selected 10 SNPs in six chromosomal regions with the strongest association (singly or as part of a haplotype) for retesting in an independent case-control set including 2,573 T2D cases and 2,776 controls. The most significant replicated result was found at the AHI1-LOC441171 gene region."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.org/dc/terms/identifier | "doi:10.1086/520599"xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Froguel P."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Nauck M."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Delplanque J."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Salonen J.T."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Mahoney W."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Meyre D."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Gibson J.M."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Kerner W."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Devine C."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Korhonen V.P."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Todorova B."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Kaikkonen J."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Tuomainen T.P."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Uimari P."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Luedemann J."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "New J.P."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Ollier W.E."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Payton A."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Darvasi A."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Pirskanen M."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Horan M.A."xsd:string |
http://purl.uniprot.org/citations/17668382 | http://purl.uniprot.org/core/author | "Pendleton N."xsd:string |