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http://purl.uniprot.org/citations/17676950 | http://www.w3.org/2000/01/rdf-schema#comment | "In this study we present a detailed, mechanism-based mathematical framework of Drosophila circadian rhythms. This framework facilitates a more systematic approach to understanding circadian rhythms using a comprehensive representation of the network underlying this phenomenon. The possible mechanisms underlying the cytoplasmic "interval timer" created by PERIOD-TIMELESS association are investigated, suggesting a novel positive feedback regulatory structure. Incorporation of this additional feedback into a full circadian model produced results that are consistent with previous experimental observations of wild-type protein profiles and numerous mutant phenotypes."xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pcbi.0030154"xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/author | "Lee K.H."xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/author | "Hong K.C."xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/author | "Garcia-Ojalvo J."xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/author | "Kuczenski R.S."xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/name | "PLoS Comput Biol"xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/pages | "e154"xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/title | "PERIOD-TIMELESS interval timer may require an additional feedback loop."xsd:string |
http://purl.uniprot.org/citations/17676950 | http://purl.uniprot.org/core/volume | "3"xsd:string |
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