| http://purl.uniprot.org/citations/17699586 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17699586 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17699586 | http://www.w3.org/2000/01/rdf-schema#comment | "Autophagy is a highly conserved, degradative process in eukaryotic cells. The rapamycin-sensitive Tor kinase complex 1 (TORC1) has a major role in regulating induction of autophagy; however, the regulatory mechanisms are not fully understood. Here, we find that the protein kinase A (PKA) and Sch9 signaling pathways regulate autophagy cooperatively in yeast. Autophagy is induced in cells when PKA and Sch9 are simultaneously inactivated. Mutant alleles of these kinases bearing a mutation that confers sensitivity to the ATP-analogue inhibitor C3-1'-naphthyl-methyl PP1 revealed that autophagy was induced independently of effects on Tor kinase. The PKA-Sch9-mediated autophagy depends on the autophagy-related 1 kinase complex, which is also essential for TORC1-regulated autophagy, the transcription factors Msn2/4, and the Rim15 kinase. The present results suggest that autophagy is controlled by the signals from at least three partly separate nutrient-sensing pathways that include PKA, Sch9, and TORC1."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e07-05-0485"xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e07-05-0485"xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/author | "Yorimitsu T."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/author | "Yorimitsu T."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/author | "Klionsky D.J."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/author | "Klionsky D.J."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/author | "Broach J.R."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/author | "Broach J.R."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/author | "Zaman S."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/author | "Zaman S."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/pages | "4180-4189"xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/pages | "4180-4189"xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/title | "Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/title | "Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/17699586 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17699586 |
| http://purl.uniprot.org/citations/17699586 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17699586 |