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http://purl.uniprot.org/citations/17705847http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17705847http://www.w3.org/2000/01/rdf-schema#comment"

Background

A large quantity of nitrogen (N) fertilizer is used for crop production to achieve high yields at a significant economic and environmental cost. Efforts have been directed to understanding the molecular basis of plant responses to N and identifying N-responsive genes in order to manipulate their expression, thus enabling plants to use N more efficiently. No studies have yet delineated these responses at the transcriptional level when plants are grown under chronic N stress and the understanding of regulatory elements involved in N response is very limited.

Results

To further our understanding of the response of plants to varying N levels, a growth system was developed where N was the growth-limiting factor. An Arabidopsis whole genome microarray was used to evaluate global gene expression under different N conditions. Differentially expressed genes under mild or severe chronic N stress were identified. Mild N stress triggered only a small set of genes significantly different at the transcriptional level, which are largely involved in various stress responses. Plant responses were much more pronounced under severe N stress, involving a large number of genes in many different biological processes. Differentially expressed genes were also identified in response to short- and long-term N availability increases. Putative N regulatory elements were determined along with several previously known motifs involved in the responses to N and carbon availability as well as plant stress.

Conclusion

Differentially expressed genes identified provide additional insights into the coordination of the complex N responses of plants and the components of the N response mechanism. Putative N regulatory elements were identified to reveal possible new components of the regulatory network for plant N responses. A better understanding of the complex regulatory network for plant N responses will help lead to strategies to improve N use efficiency."xsd:string
http://purl.uniprot.org/citations/17705847http://purl.org/dc/terms/identifier"doi:10.1186/1471-2164-8-281"xsd:string
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/author"Zhu T."xsd:string
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/author"Rothstein S.J."xsd:string
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/author"Wang R.L."xsd:string
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/author"Bi Y.M."xsd:string
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/name"BMC Genomics"xsd:string
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/pages"281"xsd:string
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/title"Global transcription profiling reveals differential responses to chronic nitrogen stress and putative nitrogen regulatory components in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/17705847http://purl.uniprot.org/core/volume"8"xsd:string
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