| http://purl.uniprot.org/citations/17761533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17761533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17761533 | http://www.w3.org/2000/01/rdf-schema#comment | "By yeast two-hybrid screening, we found three novel interactors (UNC-95, LIM-8, and LIM-9) for UNC-97/PINCH in Caenorhabditis elegans. All three proteins contain LIM domains that are required for binding. Among the three interactors, LIM-8 and LIM-9 also bind to UNC-96, a component of sarcomeric M-lines. UNC-96 and LIM-8 also bind to the C-terminal portion of a myosin heavy chain (MHC), MHC A, which resides in the middle of thick filaments in the proximity of M-lines. All interactions identified by yeast two-hybrid assays were confirmed by in vitro binding assays using purified proteins. All three novel UNC-97 interactors are expressed in body wall muscle and by antibodies localize to M-lines. Either a decreased or an increased dosage of UNC-96 results in disorganization of thick filaments. Our previous studies showed that UNC-98, a C2H2 Zn finger protein, acts as a linkage between UNC-97, an integrin-associated protein, and MHC A in myosin thick filaments. In this study, we demonstrate another mechanism by which this linkage occurs: from UNC-97 through LIM-8 or LIM-9/UNC-96 to myosin."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.E07-03-0278"xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e07-03-0278"xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Kaibuchi K."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Kaibuchi K."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Qadota H."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Qadota H."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Benian G.M."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Benian G.M."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Miller R.K."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Miller R.K."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Mercer K.B."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/author | "Mercer K.B."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/name | "Mol Biol Cell"xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/pages | "4317-4326"xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/pages | "4317-4326"xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/title | "Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/title | "Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle."xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/17761533 | http://purl.uniprot.org/core/volume | "18"xsd:string |