| http://purl.uniprot.org/citations/17852336 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17852336 | http://www.w3.org/2000/01/rdf-schema#comment | "Interferon regulatory factor-1 (IRF-1) plays important roles in host immunity, cell proliferation and apoptosis. The current GenBank sequence for human IRF-1 (accession number: L05072) was derived from a human placenta DNA library and reported in 1992. In one recent population-based sequence study, we observed consistent discrepancies between our IRF-1 sequence data and GenBank reference sequences suggesting that, current IRF-1 reference sequence was not representative for all populations. By complete gene sequencing, we obtained a representative full-length IRF-1 sequence from a single subject. Compared to submission L05072, our population-based data contains: 35 nucleotide additions, 8 nucleotide removals and another 12 nucleotide replacements. A single nucleotide difference was observed in the IRF-1 promoter sequence compared to GenBank sequence (X53095). These changes were confirmed in 350 Kenyans and 28 non-African donors. The accuracy of a reference sequence is crucial for downstream genetic and functional studies and this study provides more complete and accurate data on the sequence of the human IRF-1 gene and its immediate promoter region."xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.org/dc/terms/identifier | "doi:10.1080/10425170701606177"xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/author | "Ji H."xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/author | "Plummer F.A."xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/author | "Ball T.B."xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/author | "Kimani J."xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/author | "Liang B.B."xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/name | "DNA Seq"xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/pages | "326-331"xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/title | "Human interferon regulatory factor-1 gene and its promoter sequences revealed by population-based complete gene sequencing."xsd:string |
| http://purl.uniprot.org/citations/17852336 | http://purl.uniprot.org/core/volume | "19"xsd:string |
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