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http://purl.uniprot.org/citations/17873550http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17873550http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To assess response to physical stress, gene expression profiles in peripheral blood cells were analyzed using an original microarray carrying 1467 stress-responsive complementary DNA probes.

Design

Gene expression was analyzed at 4, 24, and 48 hours after exercising on a cycle ergometer at 60% VO2 max for 1 hour (aerobic exercise) or until exhausted (exhaustive exercise).

Setting

Institute of Health Biosciences, University of Tokushima Graduate School.

Participants

Twelve healthy male students of the postgraduate or undergraduate school.

Interventions

The volunteers performed the aerobic or exhaustive exercise on a cycle ergometer.

Main outcome measurements

Detection of aerobic exercise-responsive or exhaustive exercise-responsive genes in peripheral blood cells.

Results

Aerobic and exhaustive exercise transiently changed the expression of 21 and 16 genes, respectively, with the peak at 4 hours. Only 2 genes significantly responded to both types of exercise. Exhaustive but not aerobic exercise produced a secondary response with significantly altered expression of 14 genes at 24 hours. Five of those genes encode receptors for neurotransmitters (HTR1A, CHRNB2, GABRB3, GABRG3, and LOC51289).

Conclusions

The behavior of the individual genes shown here may be informative to objectively assess acute physical stress and exhaustion-associated responses."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.org/dc/terms/identifier"doi:10.1097/jsm.0b013e31814c3e4f"xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Kawai T."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Nishida K."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Ohta M."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Saito T."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Masuda K."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Morita K."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Nakaya Y."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Teshima-Kondo S."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Rokutan K."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/author"Sekiyama A."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/name"Clin J Sport Med"xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/pages"375-383"xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/title"Physical exercise-associated gene expression signatures in peripheral blood."xsd:string
http://purl.uniprot.org/citations/17873550http://purl.uniprot.org/core/volume"17"xsd:string
http://purl.uniprot.org/citations/17873550http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17873550
http://purl.uniprot.org/citations/17873550http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17873550
http://purl.uniprot.org/uniprot/#_A0A0H4M9X9-mappedCitation-17873550http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17873550
http://purl.uniprot.org/uniprot/#_A0A0H4M9Y0-mappedCitation-17873550http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17873550
http://purl.uniprot.org/uniprot/#_A0A0H4M9Y1-mappedCitation-17873550http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17873550
http://purl.uniprot.org/uniprot/#_A0A0H4M9Y2-mappedCitation-17873550http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17873550
http://purl.uniprot.org/uniprot/#_A0A0H4M9Y3-mappedCitation-17873550http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17873550