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http://purl.uniprot.org/citations/17874297http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17874297http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17874297http://www.w3.org/2000/01/rdf-schema#comment"Rybp (DEDAF) has been shown to interact with DED-containing proteins and to encode pro-apoptotic functions. Here we characterize a novel interaction between Rybp and Hippi, a protein implicated in neuronal apoptosis as well as in the pathogenesis of Huntington's disease. Rybp can synergize with Hippi to enhance Caspase 8-mediated apoptosis and also appears to be essential for Hippi-mediated apoptosis. Moreover, Rybp may mediate or regulate the interaction between Hippi and Caspase 8. Finally, Rybp and Hippi co-localize in a subset of neurons in the developing mouse brain. Together, these findings suggest that Rybp and Hippi may functionally interact in the apoptotic processes that accompany normal murine neural development."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.org/dc/terms/identifier"doi:10.1007/s10495-007-0131-3"xsd:string
http://purl.uniprot.org/citations/17874297http://purl.org/dc/terms/identifier"doi:10.1007/s10495-007-0131-3"xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/author"Schreiber-Agus N."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/author"Schreiber-Agus N."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/author"Locker J."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/author"Locker J."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/author"Blanck J.K."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/author"Blanck J.K."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/author"Stanton S.E."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/author"Stanton S.E."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/name"Apoptosis"xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/name"Apoptosis"xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/pages"2197-2206"xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/pages"2197-2206"xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/title"Rybp interacts with Hippi and enhances Hippi-mediated apoptosis."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/title"Rybp interacts with Hippi and enhances Hippi-mediated apoptosis."xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/17874297http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/17874297http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17874297
http://purl.uniprot.org/citations/17874297http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17874297