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http://purl.uniprot.org/citations/1788145http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1788145http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1788145http://www.w3.org/2000/01/rdf-schema#comment"An extract of chicken intestine contained neuromedin U-like immunoreactivity (36 pmol/g wet tissue weight). The primary structure of the predominant molecular form (NMU-9), comprising 94% of the total immunoreactivity, was established as: Gly-Tyr-Phe-Phe-Phe-Arg-Pro-Arg-Asn-NH2. This sequence differs from that of pig neuromedin U-8 (NMU-8) by the substitution of Leu3 by Phe and, like the corresponding peptide from the guinea pig, is extended from the NH2-terminus by a Gly residue. A minor component of neuromedin U comprised 25 amino acid residues. An extract of chicken whole brain contained much less NMU-like immunoreactivity (1.5 pmol/g) and the nonpeptide was the only molecular form detected. Synthetic chicken NMU-9 produced a concentration-dependent contraction of smooth muscle from the rat uterus and its effect was unchanged in the presence of tetrodotoxin, atropine and indomethacin. The potency of chicken NMU-9 (EC50 360 +/- 60 nM; mean +/-S.E., n = 6) was approximately 8-fold less than that of pig NMU-8 (EC50 46 +/-8 nM) but the maximum contraction produced by both agonists was not significantly different."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.org/dc/terms/identifier"doi:10.1016/0196-9781(91)90138-f"xsd:string
http://purl.uniprot.org/citations/1788145http://purl.org/dc/terms/identifier"doi:10.1016/0196-9781(91)90138-f"xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Conlon J.M."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Conlon J.M."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Zeng W."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Zeng W."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Abel P.W."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Abel P.W."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Harvey S."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Harvey S."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"O'Harte F."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"O'Harte F."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Bockman C.S."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/author"Bockman C.S."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/name"Peptides"xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/name"Peptides"xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/pages"809-812"xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/pages"809-812"xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/title"Primary structure and pharmacological activity of a nonapeptide related to neuromedin U isolated from chicken intestine."xsd:string
http://purl.uniprot.org/citations/1788145http://purl.uniprot.org/core/title"Primary structure and pharmacological activity of a nonapeptide related to neuromedin U isolated from chicken intestine."xsd:string