| http://purl.uniprot.org/citations/17888400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17888400 | http://www.w3.org/2000/01/rdf-schema#comment | "Animals and plants respond to bacterial infections and environmental stresses by inducing overlapping repertoires of defense genes. How the signals associated with infection and abiotic stresses are differentially integrated within a whole organism remains to be fully addressed. We show that the transcription of a Caenorhabditis elegans ABC transporter, pgp-5 is induced by both bacterial infection and heavy metal stress, but the magnitude and tissue distribution of its expression differs, depending on the type of stressor. PGP-5 contributes to resistance to bacterial infection and heavy metals. Using pgp-5 transcription as a read-out, we show that signals from both biotic and abiotic stresses are integrated by TIR-1, a TIR domain adaptor protein orthologous to human SARM, and a p38 MAP kinase signaling cassette. We further demonstrate that not all the TIR-1 isoforms are necessary for nematode resistance to infection, suggesting a molecular basis for the differential response to abiotic and biotic stress."xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2007.08.190"xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/author | "Baillie D.L."xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/author | "Chen K."xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/author | "Shapira M."xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/author | "Tan M.W."xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/author | "Kurz C.L."xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/pages | "438-443"xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/title | "Caenorhabditis elegans pgp-5 is involved in resistance to bacterial infection and heavy metal and its regulation requires TIR-1 and a p38 map kinase cascade."xsd:string |
| http://purl.uniprot.org/citations/17888400 | http://purl.uniprot.org/core/volume | "363"xsd:string |
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