http://purl.uniprot.org/citations/17889845 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17889845 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectivesAssessment of the diagnostic value of serum CEA, CA 15.3, osteocalcin (OC) and beta-CrossLaps (beta-CTX) in the detection of metastatic breast cancer.Design and methodsThis study included 47 patients with breast cancer (20 non-metastatic breast cancer, 11 bone metastasis, 11 soft tissue metastasis, 5 bone plus soft tissue metastasis), 10 patients with benign breast lesions and 13 healthy volunteers. CEA and CA 15.3 were determined using microparticle enzyme immunoassay; while OC and beta-CTX were measured by electrochemiluminescence immunoassay.ResultsCEA, CA 15.3, OC and beta-CTX median levels were higher in breast cancer patients compared to controls (p=0.006, 0.001, 0.004 and 0.038, respectively). Increased levels of OC and beta-CTX were demonstrated in bone metastatic patients compared to non-metastatic or soft tissue metastatic patients (p=0.000).ConclusionsCombined use of OC and beta-CTX could be useful in early detection of bone metastatic breast cancer which might improve the outcome of the disease."xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.clinbiochem.2007.07.006"xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/author | "Salem A.M."xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/author | "Abd El-Wahab M.M."xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/author | "Hamdy R."xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/author | "Zohny S.F."xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/name | "Clin Biochem"xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/pages | "1201-1208"xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/title | "Predictive value of osteocalcin and beta-CrossLaps in metastatic breast cancer."xsd:string |
http://purl.uniprot.org/citations/17889845 | http://purl.uniprot.org/core/volume | "40"xsd:string |
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