| http://purl.uniprot.org/citations/17893149 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17893149 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17893149 | http://www.w3.org/2000/01/rdf-schema#comment | "KEG1/YFR042w of Saccharomyces cerevisiae is an essential gene that encodes a 200-amino acid polypeptide with four predicted transmembrane domains. The green fluorescent protein- or Myc(6)-tagged Keg1 protein showed the typical characteristics of an integral membrane protein and was found in the endoplasmic reticulum by fluorescence imaging. Immunoprecipitation from the Triton X-100-solubilized cell lysate revealed that Keg1 binds to Kre6, which has been known to participate in beta-1,6-glucan synthesis. To analyze the essential function of Keg1 in more detail, we constructed temperature-sensitive mutant alleles by error-prone polymerase chain reaction. The keg1-1 mutant cells showed a common phenotype with Deltakre6 mutant including hypersensitivity to Calcofluor white, reduced sensitivity to the K1 killer toxin, and reduced content of beta-1,6-glucan in the cell wall. These results suggest that Keg1 and Kre6 have a cooperative role in beta-1,6-glucan synthesis in S. cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m706486200"xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m706486200"xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Sato K."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Sato K."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Kurita T."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Kurita T."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Noda Y."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Noda Y."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Yoda K."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Yoda K."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Bhuiyan M.S.A."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Bhuiyan M.S.A."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Nakamata K."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/author | "Nakamata K."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/pages | "34315-34324"xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/pages | "34315-34324"xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/title | "KEG1/YFR042w encodes a novel Kre6-binding endoplasmic reticulum membrane protein responsible for beta-1,6-glucan synthesis in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/17893149 | http://purl.uniprot.org/core/title | "KEG1/YFR042w encodes a novel Kre6-binding endoplasmic reticulum membrane protein responsible for beta-1,6-glucan synthesis in Saccharomyces cerevisiae."xsd:string |