| http://purl.uniprot.org/citations/17904530 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17904530 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17904530 | http://www.w3.org/2000/01/rdf-schema#comment | "Junctional membrane complexes (JMCs) generated by junctophilins are required for Ca(2+)-mediated communication between cell-surface and intracellular channels in excitable cells. Knockout mice lacking neural junctophilins (JP-DKO) show severe motor defects and irregular cerebellar plasticity due to abolished channel crosstalk in Purkinje cells (PCs). To precisely understand aberrations in JP-DKO mice, we further analyzed the mutant PCs. During the induction of cerebellar plasticity via electrical stimuli, JP-DKO PCs showed insufficient depolarizing responses. Immunochemistry detected mild impairment in synaptic maturation and hyperphosphorylation of protein kinase Cgamma in JP-DKO PCs. Moreover, gene expression was slightly altered in the JP-DKO cerebellum. Therefore, the mutant PCs bear marginal but widespread abnormalities, all of which likely cause cerebellar motor defects in JP-DKO mice."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2007.09.062"xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2007.09.062"xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Miyazaki T."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Miyazaki T."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Yamamoto T."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Yamamoto T."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Watanabe M."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Watanabe M."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Okuno Y."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Okuno Y."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Takeshima H."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Takeshima H."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Kakizawa S."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Kakizawa S."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Yamazaki T."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Yamazaki T."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Ikeda A."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Ikeda A."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Iino M."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Iino M."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Tsujimoto G."xsd:string |
| http://purl.uniprot.org/citations/17904530 | http://purl.uniprot.org/core/author | "Tsujimoto G."xsd:string |