Results
Your Query
▶
▶
Subject | Predicate | Object |
---|---|---|
http://purl.uniprot.org/citations/17913715 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17913715 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17913715 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectivesTo investigate the presence and distribution of integron-carrying bacteria from a slaughterhouse wastewater treatment plant (WWTP).MethodsEnterobacteriaceae and aeromonads were isolated at different stages of the wastewater treatment process and screened for the presence of integrase genes by dot-blot hybridization. Integrase-positive strains were characterized in terms of phylogenetic affiliation, genetic content of integrons and antimicrobial resistance profiles. Plasmid location of some integrons was established by Southern-blot hybridization. Strains containing integron-carrying plasmids were selected for mating experiments.ResultsIntegrase genes were present in all samples, including the final effluent. The global prevalence was determined to be 35%, higher than in other aquatic environments. Forty-two integrase-positive isolates were further characterized. Nine distinct cassette arrays were found, containing genes encoding resistance to beta-lactams (bla(OXA-30)), aminoglycosides (aadA1, aadA2, aadA13, aadB), streptothricin (sat1, sat2), trimethoprim (dfrA1, dfrA12), a putative esterase (estX) and a protein with unknown function (orfF). Gene cassette arrays aadA1, dfrAI-aadA1 and estX-sat2-aadA1 were common to aeromonads and Enterobacteriaceae. The class 2 integron containing an estX-sat2-aadA1 cassette array was detected for the first time in Aeromonas sp. Nearly 12% (5 out of 43) of intI genes were located in plasmids. intI genes from isolates MM.1.3 and MM.1.5 were successfully conjugated into Escherichia coli at frequencies of 3.79 x 10(-5) and 5.46 x 10(-5) per recipient cell, respectively.ConclusionsOur data support the hypothesis that WWTPs constitute a potential hot spot for horizontal gene transfer and for selection of antimicrobial resistance genes among aquatic bacteria. Moreover, water discharges represent a possible risk for dissemination of undesirable genetic traits."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.org/dc/terms/identifier | "doi:10.1093/jac/dkm340"xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.org/dc/terms/identifier | "doi:10.1093/jac/dkm340"xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/author | "Correia A."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/author | "Correia A."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/author | "Henriques I."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/author | "Henriques I."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/author | "Moura A."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/author | "Moura A."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/author | "Ribeiro R."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/author | "Ribeiro R."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/name | "J. Antimicrob. Chemother."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/name | "J Antimicrob Chemother"xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/pages | "1243-1250"xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/pages | "1243-1250"xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/title | "Prevalence and characterization of integrons from bacteria isolated from a slaughterhouse wastewater treatment plant."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/title | "Prevalence and characterization of integrons from bacteria isolated from a slaughterhouse wastewater treatment plant."xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/volume | "60"xsd:string |
http://purl.uniprot.org/citations/17913715 | http://purl.uniprot.org/core/volume | "60"xsd:string |
http://purl.uniprot.org/citations/17913715 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17913715 |
http://purl.uniprot.org/citations/17913715 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17913715 |