| http://purl.uniprot.org/citations/17926179 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17926179 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin-1 (IL-1) is a cytokine involved in the maturation and proliferation of B cells and plays a significant role in the development of lytic bone lesions, a major clinical feature of multiple myeloma (MM) patients. Genes that regulate products involved in the immune system are highly polymorphic and contribute to inter-individual differences that can influence the genetic predisposition and progression of particular diseases and cancers. In this study, we investigated the correlation between the single nucleotide polymorphisms IL1A -889, IL1B -511, IL1B +3954, IL1RN Mspa1 +11100 and susceptibility to MM in 74 patients and 160 controls. We found that individuals possessing IL1A -889 CT polymorphism had a higher risk in developing MM. Moreover, genotypes IL1B -511 CC, IL1B +3954 CC, IL-1RN Mspa1 +11100 CC and the combination of IL1B +3954 CC with IL1B -511 CC or IL-1RN Mspa1 +11100 CC exerted a protective effect in individuals possessing them."xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.org/dc/terms/identifier | "doi:10.1080/10428190701615892"xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/author | "Panayiotidis P."xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/author | "Tsezou A."xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/author | "Oikonomou P."xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/author | "Abazis-Stamboulieh D."xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/author | "Papadoulis N."xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/author | "Vrakidou E."xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/name | "Leuk Lymphoma"xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/pages | "2196-2203"xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/title | "Association of interleukin-1A, interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms with multiple myeloma."xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://purl.uniprot.org/core/volume | "48"xsd:string |
| http://purl.uniprot.org/citations/17926179 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17926179 |
| http://purl.uniprot.org/citations/17926179 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17926179 |
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