| http://purl.uniprot.org/citations/17928157 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17928157 | http://www.w3.org/2000/01/rdf-schema#comment | "The phenomenon of dendritic transport and local translation of mRNA is considered to be one of the most fundamental mechanisms underlying long-term synaptic plasticity. Matrix metalloproteinase 9 (gelatinase B) (MMP-9) is a matrix metalloproteinase implicated in synaptic long-term potentiation and hippocampus-dependent memory. It was recently shown to be prominently up-regulated in the hippocampal dentate gyrus (DG) upon kainate-mediated seizures. Here, using a high resolution nonradioactive in situ hybridization at the light- and electron-microscopic levels, as well as subcellular fractionation, we provide evidence that in the rat hippocampus, MMP-9 mRNA is associated with dendrites and dendritic spines bearing asymmetric (excitatory) synapses. Moreover we observe that after kainate treatment the number of dendrites and synapses containing MMP-9 mRNA increases markedly. Our results indicate that we are observing the phenomenon of dendritic transport of seizure-induced MMP-9 mRNA."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.neuroscience.2007.08.026"xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/author | "Kaczmarek L."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/author | "Konopacki F.A."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/author | "Rylski M."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/author | "Wilczynski G.M."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/author | "Wilczek E."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/author | "Amborska R."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/author | "Detka D."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/name | "Neuroscience"xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/pages | "31-39"xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/title | "Synaptic localization of seizure-induced matrix metalloproteinase-9 mRNA."xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://purl.uniprot.org/core/volume | "150"xsd:string |
| http://purl.uniprot.org/citations/17928157 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17928157 |
| http://purl.uniprot.org/citations/17928157 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17928157 |
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