| http://purl.uniprot.org/citations/17932509 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17932509 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17932509 | http://www.w3.org/2000/01/rdf-schema#comment | "Members of the Argonaute (Ago) protein family associate with small RNAs and have important roles in RNA silencing. Here, we analysed Ago1- and Ago2-containing protein complexes in human cells. Separation of Ago-associated messenger ribonucleoproteins (mRNPs) showed that Ago1 and Ago2 reside in three complexes with distinct Dicer and RNA-induced silencing complex activities. A comprehensive proteomic analysis of Ago-containing mRNPs identified a large number of proteins involved in RNA metabolism. By using co-immunoprecipitation experiments followed by RNase treatment, we biochemically mapped interactions within Ago mRNPs. Using reporter assays and knockdown experiments, we showed that the putative RNA-binding protein RBM4 is required for microRNA-guided gene regulation."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.embor.7401088"xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.embor.7401088"xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Raabe M."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Raabe M."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Kremmer E."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Kremmer E."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Meister G."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Meister G."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Urlaub H."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Urlaub H."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Ender C."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Ender C."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Hoeck J."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Hoeck J."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Ruedel S."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Ruedel S."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Weinmann L."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/author | "Weinmann L."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/17932509 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |