| http://purl.uniprot.org/citations/17938248 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17938248 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17938248 | http://www.w3.org/2000/01/rdf-schema#comment | "We have combined the proteomic analysis of Xenopus laevis in vitro-assembled chromosomes with RNA interference and live cell imaging in HeLa cells to identify novel factors required for proper chromosome segregation. The first of these is Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis. Small interfering RNA depletion of Bod1 in HeLa cells produces elongated mitotic spindles with severe biorientation defects. Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects. Bod1 depletion does not affect the activity or localization of Aurora B but does cause mislocalization of the microtubule depolymerase mitotic centromere-associated kinesin and prevents its efficient phosphorylation by Aurora B. Therefore, Bod1 is a novel kinetochore protein that is required for the detection or resolution of syntelic attachments in mitotic spindles."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200704098"xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200704098"xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Andersen J.S."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Andersen J.S."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Blow J.J."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Blow J.J."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Swedlow J.R."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Swedlow J.R."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "McAinsh A.D."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "McAinsh A.D."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Hunter C.J."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Hunter C.J."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Khoudoli G.A."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Khoudoli G.A."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "McClelland S.E."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "McClelland S.E."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Porter I.M."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/author | "Porter I.M."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/17938248 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |