| http://purl.uniprot.org/citations/17940878 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17940878 | http://www.w3.org/2000/01/rdf-schema#comment | "Prolactin (PRL) promotes maternal behavior (MB), a complex pattern of behavior aimed at maximizing offspring survival. 3alpha,5alpha-reduced neurosteroids may also regulate MB. Indeed, PRL, 3alpha,5alpha-reduced neurosteroids, and 5alpha-reductase (5alpha-R), the key enzyme in the biosynthesis of these neuroactive steroids, are all increased in stress situations These facts led us to hypothesize a possible interrelation between PRL levels and 5alpha-R. In the present study we quantified mRNA levels of both 5alpha-R isozymes in prefrontal cortex of male and female rats after administration of sulpiride, an inductor of PRL secretion. Our results demonstrated that mRNA levels of both 5alpha-R isozymes were significantly increased in male and female rats by sulpiride, directly or via sulpiride-induced hyperprolactinemia. Since 3alpha,5alpha-reduced neurosteroids and PRL exert anxiolytic effects in response to stress, these molecules and 5alpha-R may possibly participate in a common pathway of significant adaptation to stress situations."xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.org/dc/terms/identifier | "doi:10.1007/s11064-007-9512-9"xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/author | "Sanchez P."xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/author | "Ortega E."xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/author | "Torres J.M."xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/author | "Del Moral R.G."xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/author | "Vilchez P."xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/name | "Neurochem Res"xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/pages | "820-825"xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/title | "Effects of sulpiride on prolactin and mRNA levels of steroid 5alpha-reductase isozymes in adult rat brain."xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://purl.uniprot.org/core/volume | "33"xsd:string |
| http://purl.uniprot.org/citations/17940878 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17940878 |
| http://purl.uniprot.org/citations/17940878 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17940878 |
| http://purl.uniprot.org/uniprot/P31214#attribution-97D74AC43C98462307AF14223B1D1F36 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17940878 |
| http://purl.uniprot.org/uniprot/P24008#attribution-97D74AC43C98462307AF14223B1D1F36 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17940878 |
| http://purl.uniprot.org/uniprot/#_P24008-mappedCitation-17940878 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17940878 |
| http://purl.uniprot.org/uniprot/#_P31214-mappedCitation-17940878 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17940878 |
| http://purl.uniprot.org/uniprot/P24008 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17940878 |
| http://purl.uniprot.org/uniprot/P31214 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17940878 |