http://purl.uniprot.org/citations/17965155 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17965155 | http://www.w3.org/2000/01/rdf-schema#comment | "The TonB and TolA proteins are energy transducers that couple the ion electrochemical potential of the cytoplasmic membrane to support energy-dependent processes at the outer membrane of the gram-negative envelope. The transfer of energy to these transducers is facilitated by energy-harvesting complexes, which are heteromultimers of cytoplasmic membrane proteins with homologies to proton pump proteins of the flagellar motor. Although the cognate energy-harvesting complex best services each transducer, components of the complexes (for TonB, ExbB and ExbD; for TolA, TolQ and TolR) are sufficiently similar that each complex can imperfectly replace the other. Previous investigations of this molecular cross talk considered energy-harvesting complex components expressed from multicopy plasmids in strains in which the corresponding genes were interrupted by insertions, partially absent due to polarity, or missing due to a larger deletion. These questions were reexamined here using strains in which individual genes were removed by precise deletions and, where possible, components were expressed from single-copy genes with native promoters. By more closely approximating natural stoichiometries between components, this study provided insight into the roles of energy-harvesting complexes in both the energization and the stabilization of TonB. Further, the data suggest a distinct role for ExbD in the TonB energy transduction cycle."xsd:string |
http://purl.uniprot.org/citations/17965155 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.01093-07"xsd:string |
http://purl.uniprot.org/citations/17965155 | http://purl.uniprot.org/core/author | "Larsen R.A."xsd:string |
http://purl.uniprot.org/citations/17965155 | http://purl.uniprot.org/core/author | "Brinkman K.K."xsd:string |
http://purl.uniprot.org/citations/17965155 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/17965155 | http://purl.uniprot.org/core/name | "J Bacteriol"xsd:string |
http://purl.uniprot.org/citations/17965155 | http://purl.uniprot.org/core/pages | "421-427"xsd:string |
http://purl.uniprot.org/citations/17965155 | http://purl.uniprot.org/core/title | "Interactions of the energy transducer TonB with noncognate energy-harvesting complexes."xsd:string |
http://purl.uniprot.org/citations/17965155 | http://purl.uniprot.org/core/volume | "190"xsd:string |
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