| http://purl.uniprot.org/citations/17977515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17977515 | http://www.w3.org/2000/01/rdf-schema#comment | "Inherited deleterious mutations in one of the Fanconi anemia genes lead to a disease, characterized by bone marrow failure, myeloid leukemia, and hypersensitivity to DNA damage. We identified proteins likely associated to the molecular signaling pathways involved in DNA repair of interstrand cross-link lesions and in mechanisms of genomic stability mediated by FA/BRCA pathways. We compared protein maps resolved by bidimensional electrophoresis and analyzed differentially expressed proteins, by mass spectrometry, between FA complementation group C (FANCC)-deficient cells, and their ectopically corrected counterpart in physiological conditions or after treatment with MMC. We found six differentially expressed proteins; among them, the checkpoint mediator protein MDC1 whose expression was disrupted in FANCC-/-cells. The potential role of differentially expressed proteins in FA phenotype is discussed."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2007.10.025"xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/author | "Seuanez H.N."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/author | "Paixao J.C."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/author | "Bisch P.M."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/author | "Cabral-Neto J.B."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/author | "Pizzatti L."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/author | "Cabral R.E."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/author | "Salles D."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/author | "de Almeida C.E."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/pages | "755-760"xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/title | "Changes in protein expression due to deleterious mutations in the FA/BRCA pathway."xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://purl.uniprot.org/core/volume | "364"xsd:string |
| http://purl.uniprot.org/citations/17977515 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17977515 |
| http://purl.uniprot.org/citations/17977515 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17977515 |
| http://purl.uniprot.org/uniprot/#_A0A0F6TMZ9-mappedCitation-17977515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17977515 |
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| http://purl.uniprot.org/uniprot/#_A0A0F6TN92-mappedCitation-17977515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17977515 |
| http://purl.uniprot.org/uniprot/#_A0A068BDS2-mappedCitation-17977515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17977515 |
| http://purl.uniprot.org/uniprot/#_A0A068BDS6-mappedCitation-17977515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17977515 |
| http://purl.uniprot.org/uniprot/#_A0A068BDT0-mappedCitation-17977515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17977515 |
| http://purl.uniprot.org/uniprot/#_A0A068BDU2-mappedCitation-17977515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17977515 |