| http://purl.uniprot.org/citations/17979836 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17979836 | http://www.w3.org/2000/01/rdf-schema#comment | "Death receptors (DRs) are more than simple killers: they control cell growth, proliferation, and survival, thereby playing a pivotal role in immune and inflammatory responses. Some of these phenomena might be explained by aberrant reactive oxygen species (ROS) production and metabolism, which can lead to oxidative stress. A key signaling molecule of DR-initiated intracellular pathways, receptor-interacting protein 1 (RIP1), orchestrates a complex control of multiple responses and may link DR-associated signaling complexes to ROS production by mitochondria. Yet, RIP1 is also an important regulator of endogenous anti-oxidants and ROS scavenging enzymes, because it is required for nuclear factor kappaB activation that results in expression of anti-apoptotic and anti-oxidant proteins. Alteration of RIP1 function may result in ROS accumulation and abnormal c-Jun N-terminal protein kinase activation, affecting inflammatory responses, innate immunity, stress responses, and cell survival. These molecular mechanisms may be involved in neoplastic, autoimmune, neurodegenerative, inflammatory, and metabolic diseases."xsd:string |
| http://purl.uniprot.org/citations/17979836 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1600-065x.2007.00560.x"xsd:string |
| http://purl.uniprot.org/citations/17979836 | http://purl.uniprot.org/core/author | "Karin M."xsd:string |
| http://purl.uniprot.org/citations/17979836 | http://purl.uniprot.org/core/author | "Temkin V."xsd:string |
| http://purl.uniprot.org/citations/17979836 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17979836 | http://purl.uniprot.org/core/name | "Immunol Rev"xsd:string |
| http://purl.uniprot.org/citations/17979836 | http://purl.uniprot.org/core/pages | "8-21"xsd:string |
| http://purl.uniprot.org/citations/17979836 | http://purl.uniprot.org/core/title | "From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey."xsd:string |
| http://purl.uniprot.org/citations/17979836 | http://purl.uniprot.org/core/volume | "220"xsd:string |
| http://purl.uniprot.org/citations/17979836 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17979836 |
| http://purl.uniprot.org/citations/17979836 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17979836 |
| http://purl.uniprot.org/uniprot/Q13546#attribution-4CF03424D92486506CF57B0AA7705AFC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17979836 |