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http://purl.uniprot.org/citations/17981364http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17981364http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17981364http://www.w3.org/2000/01/rdf-schema#comment"A novel peptide, decoralin, was isolated from the venom of the solitary eumenine wasp Oreumenes decoratus. Its sequence, Ser-Leu-Leu-Ser-Leu-Ile-Arg-Lys-Leu-Ile-Thr, was determined by Edman degradation and corroborated by solid-phase synthesis. This sequence has the characteristic features of linear cationic alpha-helical peptides; rich in hydrophobic and basic amino acids with no disulfide bond, and accordingly, it can be predicted to adopt an amphipathic alpha-helix secondary structure. In fact, the CD spectra of decoralin in the presence of TFE or SDS showed a high alpha-helical conformation content. In a biological evaluation, decoralin exhibited a significant broad-spectrum antimicrobial activity, and moderate mast cell degranulation and leishmanicidal activities, but showed virtually no hemolytic activity. A synthetic analog with C-terminal amidation showed a much more potent activity in all the biological assays."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.org/dc/terms/identifier"doi:10.1016/j.peptides.2007.09.017"xsd:string
http://purl.uniprot.org/citations/17981364http://purl.org/dc/terms/identifier"doi:10.1016/j.peptides.2007.09.017"xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Mori K."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Mori K."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Oliveira J.S."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Oliveira J.S."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Kawano M."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Kawano M."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Nakata Y."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Nakata Y."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Fontana R."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Fontana R."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Konno K."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Konno K."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Dos Santos Cabrera M.P."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Dos Santos Cabrera M.P."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Hirata I.Y."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Hirata I.Y."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Neto J.R."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Neto J.R."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Rangel M."xsd:string
http://purl.uniprot.org/citations/17981364http://purl.uniprot.org/core/author"Rangel M."xsd:string