http://purl.uniprot.org/citations/17984573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17984573 | http://www.w3.org/2000/01/rdf-schema#comment | "Adiponectin is an adipocytokine that is involved in insulin sensitivity. The adiponectin gene contains a single nucleotide polymorphism (SNP) at position 276 (G/T). The GG genotype of SNP276 (G/T) is associated with lower plasma adiponectin levels and a higher insulin resistance index. Therefore, we examined the influence of SNP276 (G/T) on the plasma level of adiponectin in response to exercise training. Thirty healthy Japanese (M12/F18; 56 to 79 years old) performed both resistance and endurance training, 5 times a week for 6 months. The work rate per kg of weight at double-product break-point (DPBP) was measured. Blood samples were obtained before and after the experiment. Plasma concentrations of adiponectin, HbA1c, insulin, glucose, total, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) cholesterol, and triglyceride were measured. Genotypes of SNP276 were specified. Student's t-test for paired values and unpaired values was used. After the 6-month training period, the work rate per kg of weight at DPBP and the plasma HDL-cholesterol level were significantly improved (P<0.05), while no change was observed in the total plasma adiponectin level. However, the plasma adiponectin level in those with the GT + TT genotype had significantly increased (P<0.05). Additionally, the degree of the decrease in the HOMA-R level was significantly greater in the subjects with the GT + TT genotype than those with the GG genotype (p<0.05). Our results suggest that subjects with the genotype GT + TT at SNP276 (G/T) have a greater adiponectin-related response to exercise training than those with the GG genotype."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.org/dc/terms/identifier | "doi:10.1507/endocrj.k06-146"xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Huang H."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Maeda S."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Murakami H."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Otsuki T."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Saito Y."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Kuno S."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Sone H."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Iemitsu M."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Ajisaka R."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/author | "Tada Iida K."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/name | "Endocr J"xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/pages | "879-886"xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/title | "Influence of adiponectin gene polymorphism SNP276 (G/T) on adiponectin in response to exercise training."xsd:string |
http://purl.uniprot.org/citations/17984573 | http://purl.uniprot.org/core/volume | "54"xsd:string |
http://purl.uniprot.org/citations/17984573 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17984573 |
http://purl.uniprot.org/citations/17984573 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17984573 |
http://purl.uniprot.org/uniprot/#_A8K660-mappedCitation-17984573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17984573 |
http://purl.uniprot.org/uniprot/#_B2R773-mappedCitation-17984573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17984573 |
http://purl.uniprot.org/uniprot/#_Q15848-mappedCitation-17984573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17984573 |
http://purl.uniprot.org/uniprot/B2R773 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17984573 |
http://purl.uniprot.org/uniprot/A8K660 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17984573 |