| http://purl.uniprot.org/citations/17989341 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17989341 | http://www.w3.org/2000/01/rdf-schema#comment | "The immune system may interplay between Chlamydia pneumoniae infection and coronary artery disease (CAD). Major histocompatibility complex genes regulate innate and adaptive immunity. Patients with CAD (n = 100) and controls (n = 74) were enrolled. Human leukocyte antigens (HLA-A, HLA-B, and HLA-DRB1), four lymphotoxin alpha single-nucleotide polymorphisms, and complement C4A and C4B allotypes were typed, and their haplotypes were inferred. The presence of serum C. pneumoniae immunoglobulin A (IgA) (titer, > or =40) or IgG (titer, > or =128) antibodies or immune complex (IC)-bound IgG antibodies (titer, > or =2) was considered to be a serological marker suggesting chronic C. pneumoniae infection. C. pneumoniae IgA antibodies were found more frequently in patients than in controls (P = 0.04). Among the patients, multiple logistic regression analysis showed the HLA-B*35 allele to be the strongest-risk gene for C. pneumoniae infection (odds ratio, 7.88; 95% confidence interval, 2.44 to 25.43; P = 0.0006). Markers of C. pneumoniae infection were found more frequently in patients with the HLA-A*03-B*35 haplotype than in those without the haplotype (P = 0.007 for IgA; P = 0.008 for IgG; P = 0.002 for IC). Smokers with HLA-B*35 or HLA-A*03-B*35 had markers of C. pneumoniae infection that appeared more often than in smokers without these genes (P = 0.003 and P = 0.001, respectively). No associations were found in controls. In conclusion, HLA-B*35 may be the link between chronic C. pneumoniae infection and CAD."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.org/dc/terms/identifier | "doi:10.1128/cvi.00163-07"xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Lokki M.L."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Nieminen M.S."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Sinisalo J."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Leinonen M."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Seppanen M."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Saikku P."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Palikhe A."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Valtonen V."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/author | "Paldanius M."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/name | "Clin Vaccine Immunol"xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/pages | "55-59"xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/title | "Association of Chlamydia pneumoniae infection with HLA-B*35 in patients with coronary artery disease."xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/17989341 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17989341 |
| http://purl.uniprot.org/citations/17989341 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17989341 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-17989341 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17989341 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-17989341 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17989341 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-17989341 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17989341 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-17989341 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17989341 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-17989341 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17989341 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DCA1-mappedCitation-17989341 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17989341 |