| http://purl.uniprot.org/citations/17996944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17996944 | http://www.w3.org/2000/01/rdf-schema#comment | "Granzyme B and perforin are the major protagonists of cytotoxicity mediated by natural killer (NK) cells or cytotoxic T cells. More recent we described the presence of granzyme B and perforin in polymorphonuclear neutrophils (PMN), a finding in discrepancy with the credo that granzyme B and perforin expression is restricted to cytotoxic T cells and NK cells. In extension of our previous study, we now provide evidence that granzyme B is not only present in mature PMN, but also in the myeloid cell lines HL-60 and U937, in CD34+ stem cells, and in PMN derived from CD34+ cells in vitro. In agreement with the "targeting by time" hypothesis we found the bulk of granzyme B in association with primary granules, in addition to a minor membrane expression. Granzyme B, on one hand might, enhance the cytotoxic potential of PMN, on the other, it may provide PMN with additional means to degrade extracellular matrices."xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molimm.2007.09.033"xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://purl.uniprot.org/core/author | "Wagner C."xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://purl.uniprot.org/core/author | "Stegmaier S."xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://purl.uniprot.org/core/author | "Hansch G.M."xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/17996944 | http://purl.uniprot.org/core/name | "Mol Immunol"xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://purl.uniprot.org/core/pages | "1761-1766"xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://purl.uniprot.org/core/title | "Expression of granzyme B in peripheral blood polymorphonuclear neutrophils (PMN), myeloid cell lines and in PMN derived from haemotopoietic stem cells in vitro."xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://purl.uniprot.org/core/volume | "45"xsd:string |
| http://purl.uniprot.org/citations/17996944 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17996944 |
| http://purl.uniprot.org/citations/17996944 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17996944 |
| http://purl.uniprot.org/uniprot/#_P10144-mappedCitation-17996944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/#_J3KQ52-mappedCitation-17996944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/#_Q67BC3-mappedCitation-17996944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/#_Q6XGZ2-mappedCitation-17996944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/#_Q6XGZ3-mappedCitation-17996944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/#_Q6XGZ4-mappedCitation-17996944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/P10144 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/J3KQ52 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/Q6XGZ2 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/Q6XGZ4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/Q67BC3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17996944 |
| http://purl.uniprot.org/uniprot/Q6XGZ3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17996944 |