| http://purl.uniprot.org/citations/18003861 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18003861 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18003861 | http://www.w3.org/2000/01/rdf-schema#comment | "Small RNAs, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), are essential regulatory molecules of many cellular processes. Arabidopsis has at least three classes of endogenous siRNAs--chromatin-associated siRNAs, trans-acting siRNAs (tasiRNAs), and natural antisense transcript (NAT)-associated siRNAs (nat-siRNAs)--all 20-25 nucleotides (nt) in length. Here, we identified a novel class of small RNAs, long siRNAs (lsiRNAs), which are 30-40 nt and share many common features with known siRNAs. The lsiRNAs identified so far are induced by pathogen infection or under specific growth conditions. One of the lsiRNAs, AtlsiRNA-1, is generated from SRRLK/AtRAP NAT pair and specifically induced by the bacterium Pseudomonas syringae carrying effector avrRpt2. Recently, 25-to 31-nt PIWI-interacting RNAs (piRNAs) and repeat-associated siRNAs (rasiRNAs) were identified in animal germline cells. In contrast to the biogenesis of piRNAs/rasiRNAs, which is dicer independent and requires PIWI subfamily proteins, generation of AtlsiRNA-1 requires DCL1, DCL4, and the ARGONAUTE subfamily protein AGO7. It also depends on HYL1, HEN1, HST1, RDR6, and Pol IV. Induction of AtlsiRNA-1 silences AtRAP, which encodes a RAP-domain protein involved in disease resistance. Our further analysis implies that AtlsiRNA-1 may destabilize target mRNA through decapping and XRN4-mediated 5'-to-3' degradation."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.1595107"xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.1595107"xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/author | "Jin H."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/author | "Jin H."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/author | "Gao S."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/author | "Gao S."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/author | "Katiyar-Agarwal S."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/author | "Katiyar-Agarwal S."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/author | "Vivian-Smith A."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/author | "Vivian-Smith A."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/pages | "3123-3134"xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/pages | "3123-3134"xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/title | "A novel class of bacteria-induced small RNAs in Arabidopsis."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/title | "A novel class of bacteria-induced small RNAs in Arabidopsis."xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/volume | "21"xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://purl.uniprot.org/core/volume | "21"xsd:string |
| http://purl.uniprot.org/citations/18003861 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18003861 |
| http://purl.uniprot.org/citations/18003861 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18003861 |