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| http://purl.uniprot.org/citations/18037380 | http://www.w3.org/2000/01/rdf-schema#comment | "Cholesterol is one of the major lipids of plasma membranes. Recently, we have shown that cholesterol depletion by methyl-beta-cyclodextrin (M beta CD) induces the activation of the Wnt/beta-catenin pathway and enhances myogenic differentiation. Here, we show that M beta CD-conditioned media accelerates myogenesis in a similar way as M beta CD does, suggesting that the effects induced by M beta CD could be caused by soluble factors present in the culture medium. Soluble Wnt-3 protein is significantly enhanced in M beta CD-conditioned medium. Wnt-3a-enriched media induces myogenesis as much as M beta CD does, whereas Wnt-5a-enriched media inhibits. We suggest that Wnt-3a is involved in the myogenic induction observed after cholesterol depletion."xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2007.11.047"xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/author | "Costa M.L."xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/author | "Martins E.R."xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/author | "Mermelstein C.S."xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/author | "Portilho D.M."xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/pages | "5787-5795"xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/title | "A soluble and active form of Wnt-3a protein is involved in myogenic differentiation after cholesterol depletion."xsd:string |
| http://purl.uniprot.org/citations/18037380 | http://purl.uniprot.org/core/volume | "581"xsd:string |
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