| http://purl.uniprot.org/citations/18056920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18056920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18056920 | http://www.w3.org/2000/01/rdf-schema#comment | "Proteins present in the seminal fluid of Drosophila melanogaster (accessory gland proteins Acps) contribute to female postmating behavioral changes, sperm storage, sperm competition, and immunity. Consequently, male-female coevolution and host-pathogen interactions are thought to underlie the rapid, adaptive evolution that characterizes several Acp-encoding genes. We propose that seminal fluid proteases are likely targets of selection due to their demonstrated or potential roles in between-sex interactions and immune processes. We use within- and between-species sequence data for 5 predicted protease-encoding Acp loci to test this hypothesis. Our polymorphism-based analyses find evidence for positive selection at 2 genes, both of which encode predicted serine protease homologs. One of these genes, CG6069, also shows evidence for consistent selection on a subset of codons over a deeper evolutionary time scale. The second gene, CG9997, was previously shown to be essential for normal sperm usage, suggesting that sexual selection may underlie its history of adaptation."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.org/dc/terms/identifier | "doi:10.1093/molbev/msm270"xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.org/dc/terms/identifier | "doi:10.1093/molbev/msm270"xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/author | "Aquadro C.F."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/author | "Aquadro C.F."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/author | "Wolfner M.F."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/author | "Wolfner M.F."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/author | "Wong A."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/author | "Wong A."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/author | "Turchin M.C."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/author | "Turchin M.C."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/name | "Mol. Biol. Evol."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/name | "Mol Biol Evol"xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/pages | "497-506"xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/pages | "497-506"xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/title | "Evidence for positive selection on Drosophila melanogaster seminal fluid protease homologs."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/title | "Evidence for positive selection on Drosophila melanogaster seminal fluid protease homologs."xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/volume | "25"xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://purl.uniprot.org/core/volume | "25"xsd:string |
| http://purl.uniprot.org/citations/18056920 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18056920 |
| http://purl.uniprot.org/citations/18056920 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18056920 |