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http://purl.uniprot.org/citations/18060866http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18060866http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18060866http://www.w3.org/2000/01/rdf-schema#comment"Small GTPases act as molecular switches in a wide variety of cellular processes. In fission yeast Schizosaccharomyces pombe, the directions of cell growth change from a monopolar manner to a bipolar manner, which is known as 'New End Take Off' (NETO). Here I report the identification of a gene, arf6(+), encoding an ADP-ribosylation factor small GTPase, that may be essential for NETO. arf6Delta cells completely fail to undergo NETO. arf6p localizes at both cell ends and presumptive septa in a cell-cycle dependent manner. And its polarized localization is not dependent on microtubules, actin cytoskeletons and some NETO factors (bud6p, for3p, tea1p, tea3p, and tea4p). Notably, overexpression of a fast GDP/GTP-cycling mutant of arf6p can advance the timing of NETO. These findings suggest that arf6p functions as a molecular switch for the activation of NETO in fission yeast."xsd:string
http://purl.uniprot.org/citations/18060866http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2007.11.117"xsd:string
http://purl.uniprot.org/citations/18060866http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2007.11.117"xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/author"Fujita A."xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/author"Fujita A."xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/pages"193-198"xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/pages"193-198"xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/title"ADP-ribosylation factor arf6p may function as a molecular switch of new end take off in fission yeast."xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/title"ADP-ribosylation factor arf6p may function as a molecular switch of new end take off in fission yeast."xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/volume"366"xsd:string
http://purl.uniprot.org/citations/18060866http://purl.uniprot.org/core/volume"366"xsd:string
http://purl.uniprot.org/citations/18060866http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/18060866
http://purl.uniprot.org/citations/18060866http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/18060866
http://purl.uniprot.org/citations/18060866http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/18060866
http://purl.uniprot.org/citations/18060866http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/18060866
http://purl.uniprot.org/uniprot/Q9Y7Z2http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/18060866
http://purl.uniprot.org/uniprot/Q9Y7Z2#attribution-765C952B910CA2356D0DD6C2DC7F140Bhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18060866
http://purl.uniprot.org/uniprot/Q9Y7Z2#attribution-A798122644AE3E89D0FDF4CEDB03A640http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18060866
http://purl.uniprot.org/uniprot/Q9Y7Z2#attribution-C3557937979A6653D2203D3B015753DBhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18060866