| http://purl.uniprot.org/citations/18077433 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18077433 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18077433 | http://www.w3.org/2000/01/rdf-schema#comment | "We have previously reported that a 2.1-kb homology (H) sequence, conserved between mouse and human, regulates the odorant receptor (OR) gene MOR28 in transgenic mice. Here, we narrowed down the essential sequences of the H to a core of 124 bp by using a transient expression system in zebrafish embryos. Transgenic experiments in mice demonstrated that the core-H sequence is sufficient to endow expression of the MOR28 minigene. Deletion and mutation analyses of the core-H region revealed two homeodomain sequences to be essential for the H enhancer activity. Targeted deletion of the core-H abolished expression of three proximal OR genes, MOR28, MOR10, and MOR83, in cis, indicating the presence of another locus control region/enhancer in the downstream region, that regulates four distal OR genes in the same MOR28 cluster. In the heterozygous mice, the H(-) phenotype of the mutant allele was not rescued by the wild-type H(+) allele in trans."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0706544105"xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Inoue N."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Inoue N."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Sakano H."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Sakano H."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Nakashima A."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Nakashima A."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Nishizumi H."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Nishizumi H."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Kumasaka K."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/author | "Kumasaka K."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/pages | "20067-20072"xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/pages | "20067-20072"xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/title | "Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/title | "Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis."xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/volume | "104"xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://purl.uniprot.org/core/volume | "104"xsd:string |
| http://purl.uniprot.org/citations/18077433 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18077433 |