| http://purl.uniprot.org/citations/18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18089500 | http://www.w3.org/2000/01/rdf-schema#comment | "Progression of follicular lymphoma (FL) to a higher-grade lymphoma occurs in 25% to 60% of cases and frequently indicates a poor prognosis. The transformation is accompanied by alteration in morphologic features and clinical behaviors. Herein, we report a case of FL occurring in a 59-year-old woman with the development of a precursor B-cell lymphoblastic lymphoma (PBC-LBL) during a 6-month period. Both lymphomas had identical bcl-2 and immunoglobulin heavy-chain gene breakpoints as assessed by polymerase chain reaction amplification and direct sequencing, indicating that the 2 tumors originated from a common precursor B-cell clone or the PBC-LBL arose from clonal evolution of its preceding FL and "dedifferentiated" into a lymphoblastic stage. Immunohistochemical studies revealed that both lymphomas displayed typical phenotypic characteristics. A c-myc gene translocation was observed in the PBC-LBL but not the FL by fluorescence in situ hybridization. The c-myc translocation is also reported in similar cases in the literature and likely is crucial in the pathogenesis of the PBC-LBL."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.org/dc/terms/identifier | "doi:10.1309/nkk3fex2be5l7ekb"xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/author | "Zhou G."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/author | "Xie Q."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/author | "Chan W.C."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/author | "Sanger W.G."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/author | "Young K.H."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/author | "Eickhoff J.C."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/author | "Aoun P."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/name | "Am J Clin Pathol"xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/pages | "157-166"xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/title | "Transformation of follicular lymphoma to precursor B-cell lymphoblastic lymphoma with c-myc gene rearrangement as a critical event."xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://purl.uniprot.org/core/volume | "129"xsd:string |
| http://purl.uniprot.org/citations/18089500 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18089500 |
| http://purl.uniprot.org/citations/18089500 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18089500 |
| http://purl.uniprot.org/uniprot/#_A0A0B4J1R1-mappedCitation-18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18089500 |
| http://purl.uniprot.org/uniprot/#_A0N2G3-mappedCitation-18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18089500 |
| http://purl.uniprot.org/uniprot/#_A0A224B085-mappedCitation-18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18089500 |
| http://purl.uniprot.org/uniprot/#_B3CJ86-mappedCitation-18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18089500 |
| http://purl.uniprot.org/uniprot/#_B3CJ87-mappedCitation-18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18089500 |
| http://purl.uniprot.org/uniprot/#_B3CJ88-mappedCitation-18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18089500 |
| http://purl.uniprot.org/uniprot/#_B3CJB3-mappedCitation-18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18089500 |
| http://purl.uniprot.org/uniprot/#_B3CJB8-mappedCitation-18089500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18089500 |