| http://purl.uniprot.org/citations/18162590 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18162590 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18162590 | http://www.w3.org/2000/01/rdf-schema#comment | "Protein dephosphorylation by the serine/threonine protein phosphatase 2A (PP2A) modulates a broad array of cellular functions. PP2A normally acts as a heterotrimeric holoenzyme complex comprising a catalytic subunit bound by regulatory A and B subunits. Characterization of the regulatory A subunit isoforms (ROOTS CURL IN NAPHTHYLPHTHALAMIC ACID1 [RCN1], PP2AA2, and PP2AA3) of Arabidopsis thaliana PP2A has shown that RCN1 plays a primary role in controlling root and hypocotyl PP2A activity in seedlings. Here we show that hypocotyl and root growth exhibit different requirements for RCN1-mediated regulation of PP2A activity. Roots of rcn1 mutant seedlings exhibit characteristic abnormalities in cell division patterns at the root apical meristem, as well as reduced growth under ionic, osmotic, and oxidative stress conditions. We constructed chimeric A subunit genes and found that restoration of normal root tip development in rcn1 plants requires both regulatory and coding sequences of RCN1, whereas the hypocotyl elongation defect of rcn1 plants can be complemented by either RCN1 or PP2AA3 transgenes. Furthermore, the RCN1 and PP2AA3 proteins exhibit ubiquitous subcellular localization patterns in seedlings and both associate with membrane compartments. Together, these results show that RCN1-containing PP2A has unique functions that cannot be attributed to isoform-specific expression and localization patterns. Postembryonic RCN1 function is required to maintain normal auxin distribution and stem cell function at the root apex. Our data show that RCN1-regulated phosphatase activity plays a unique role in regulating postembryonic root development and stress response."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.org/dc/terms/identifier | "doi:10.1104/pp.107.112995"xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.org/dc/terms/identifier | "doi:10.1104/pp.107.112995"xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "DeLong A."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "DeLong A."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Blakeslee J.J."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Blakeslee J.J."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Zhou H.W."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Zhou H.W."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Barrios J.A."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Barrios J.A."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Heath J.T."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Heath J.T."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Liu S.Y."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Liu S.Y."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Skottke K.R."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/author | "Skottke K.R."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/name | "Plant Physiol."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/name | "Plant Physiol."xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/pages | "539-553"xsd:string |
| http://purl.uniprot.org/citations/18162590 | http://purl.uniprot.org/core/pages | "539-553"xsd:string |