| http://purl.uniprot.org/citations/18167337 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18167337 | http://www.w3.org/2000/01/rdf-schema#comment | "Aberrant TGFbeta signaling is common in human cancers and contributes to tumor metastasis. Here, we demonstrate that Gr-1+CD11b+ myeloid cells are recruited into mammary carcinomas with type II TGF beta receptor gene (Tgfbr2) deletion and directly promote tumor metastasis. Gr-1+CD11b+ cells infiltrate into the invasive front of tumor tissues and facilitate tumor cell invasion and metastasis through a process involving metalloproteinase activity. This infiltration of Gr-1+CD11b+ cells also results in increased abundance of TGF beta 1 in tumors with Tgfbr2 deletion. The recruitment of Gr-1+CD11b+ cells into tumors with Tgfbr2 deletion involves two chemokine receptor axes, the SDF-1/CXCR4 and CXCL5/CXCR2 axes. Together, these data indicate that Gr-1+CD11b+ cells contribute to TGFbeta-mediated metastasis through enhancing tumor cell invasion and metastasis."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ccr.2007.12.004"xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Huang J."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Ren X."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Yang L."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Richmond A."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Chytil A."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Moses H.L."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Lin P.C."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Matrisian L.M."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Gorska A.E."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Carbone D.P."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/author | "Aakre M."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/name | "Cancer Cell"xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/pages | "23-35"xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/title | "Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis."xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/18167337 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18167337 |
| http://purl.uniprot.org/citations/18167337 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18167337 |
| http://purl.uniprot.org/uniprot/#_Q62312-mappedCitation-18167337 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18167337 |
| http://purl.uniprot.org/uniprot/#_Q3UG22-mappedCitation-18167337 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18167337 |
| http://purl.uniprot.org/uniprot/#_Q8BQS9-mappedCitation-18167337 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18167337 |
| http://purl.uniprot.org/uniprot/#_Q78JJ8-mappedCitation-18167337 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18167337 |