| http://purl.uniprot.org/citations/18204463 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18204463 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18204463 | http://www.w3.org/2000/01/rdf-schema#comment | "Regulators of G-protein signaling (RGS) proteins enhance the intrinsic GTPase activity of G protein alpha (Galpha) subunits and are vital for proper signaling kinetics downstream of G protein-coupled receptors (GPCRs). R7 subfamily RGS proteins specifically and obligately dimerize with the atypical G protein beta5 (Gbeta5) subunit through an internal G protein gamma (Ggamma)-subunit-like (GGL) domain. Here we present the 1.95-A crystal structure of the Gbeta5-RGS9 complex, which is essential for normal visual and neuronal signal transduction. This structure reveals a canonical RGS domain that is functionally integrated within a molecular complex that is poised for integration of multiple steps during G-protein activation and deactivation."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb.1377"xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb.1377"xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Siderovski D.P."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Siderovski D.P."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Sondek J."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Sondek J."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Harden T.K."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Harden T.K."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Gershburg S."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Gershburg S."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Cheever M.L."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Cheever M.L."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Snyder J.T."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/author | "Snyder J.T."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/name | "Nat. Struct. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/name | "Nat. Struct. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/pages | "155-162"xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/pages | "155-162"xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/title | "Crystal structure of the multifunctional Gbeta5-RGS9 complex."xsd:string |
| http://purl.uniprot.org/citations/18204463 | http://purl.uniprot.org/core/title | "Crystal structure of the multifunctional Gbeta5-RGS9 complex."xsd:string |