| http://purl.uniprot.org/citations/18204858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18204858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18204858 | http://www.w3.org/2000/01/rdf-schema#comment | "Transcription factor Dd-STATa, a functional Dictyostelium homologue of metazoan signal transducers and activators of transcription proteins, is necessary for culmination during development. We have isolated more than 18 putative multicopy suppressors of Dd-STATa using genetic screening. One was hssA gene, whose expression is known to be G-box-binding-factor-dependent and which was specific to prestalk A (pstA) cells, where Dd-STATa is activated. Also, hssA mRNA was expressed in pstA cells in the Dd-STATa-null mutant. At least 40 hssA-related genes are present in the genome and constitute a multigene family. The tagged HssA protein was translated; hssA encodes an unusually high-glycine-serine-rich small protein (8.37 kDa), which has strong homology to previously reported cyclic-adenosine-monophosphate-inducible 2C and 7E proteins. Overexpression of hssA mRNA as well as frame-shifted versions of hssA RNA suppressed the phenotype of the partially active Dd-STATa strain, suggesting that translation is not necessary for suppression. Although overexpression of prespore-specific genes among the family did not suppress the parental phenotype, prestalk-specific family members did. Although overexpression of the hssA did not revert the expression of Dd-STATa target genes, and although its suppression mechanism remains unknown, morphological reversion implies functional relationships between Dd-STATa and hssA."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00427-008-0202-7"xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00427-008-0202-7"xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/author | "Kawata T."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/author | "Kawata T."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/author | "Shimada N."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/author | "Shimada N."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/author | "Kanno-Tanabe N."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/author | "Kanno-Tanabe N."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/author | "Minemura K."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/author | "Minemura K."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/name | "Dev. Genes Evol."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/name | "Dev. Genes Evol."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/pages | "55-68"xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/pages | "55-68"xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/title | "GBF-dependent family genes morphologically suppress the partially active Dictyostelium STATa strain."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/title | "GBF-dependent family genes morphologically suppress the partially active Dictyostelium STATa strain."xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/volume | "218"xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://purl.uniprot.org/core/volume | "218"xsd:string |
| http://purl.uniprot.org/citations/18204858 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18204858 |
| http://purl.uniprot.org/citations/18204858 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18204858 |