http://purl.uniprot.org/citations/18221262 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18221262 | http://www.w3.org/2000/01/rdf-schema#comment | "Myosin V is an actin-based motor essential for a variety of cellular processes including skin pigmentation, cell separation and synaptic transmission. Myosin V transports organelles, vesicles and mRNA by binding, directly or indirectly, to cargo-bound receptors via its C-terminal globular tail domain (GTD). We have used the budding yeast myosin V Myo2p to shed light on the mechanism of how Myo2p interacts with post-Golgi carriers. We show that the Rab/Ypt protein Ypt32p, which associates with membranes of the trans-Golgi network, secretory vesicles and endosomes and is related to the mammalian Rab11, interacts with the Myo2p GTD within a region previously identified as the 'vesicle binding region'. Furthermore, we show that the essential myosin light chain 1 (Mlc1p), required for vesicle delivery at the mother-bud neck during cytokinesis, binds to the Myo2p GTD in a region overlapping that of Ypt32p. Our data are consistent with a role of Ypt32p and Mlc1p in regulating the interaction of post-Golgi carriers with Myo2p subdomain II."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2958.2008.06106.x"xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/author | "Cicero D.O."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/author | "Bielli P."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/author | "Ragnini-Wilson A."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/author | "Porcu G."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/author | "Di Pentima A."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/author | "Pennestri M."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/author | "Casavola E.C."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/author | "Catucci A."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/name | "Mol Microbiol"xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/pages | "1051-1066"xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/title | "Ypt32p and Mlc1p bind within the vesicle binding region of the class V myosin Myo2p globular tail domain."xsd:string |
http://purl.uniprot.org/citations/18221262 | http://purl.uniprot.org/core/volume | "67"xsd:string |
http://purl.uniprot.org/citations/18221262 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18221262 |
http://purl.uniprot.org/citations/18221262 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18221262 |
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