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http://purl.uniprot.org/citations/18236010http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18236010http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18236010http://www.w3.org/2000/01/rdf-schema#comment"Plant isoprenoids are derived from two independent pathways, the cytosolic mevalonate pathway and the plastid methylerythritol 4-phosphate (MEP) pathway. We used green fluorescent fusion protein assays to demonstrate that the Arabidopsis MEP pathway enzymes are localized to the chloroplast. We have also characterized three Arabidopsis albino mutants, ispD-1, ispD-2 and ispE-1, which have T-DNA insertions in the IspD and IspE genes of the MEP pathway. Levels of photosynthetic pigments are almost undetectable in these albino mutants. Instead of thylakoids, the ispD and ispE mutant chloroplasts are filled with large vesicles. Impairments in chloroplast development and functions may signal changes in the expression of nuclear, chloroplast and mitochondrial genes. We used northern blot analysis to examine the expression of photosynthetic and respiratory genes in the ispD and ispE albino mutants. Steady-state mRNA levels of nucleus- and chloroplast-encoded photosynthetic genes are significantly decreased in the albino mutants. In contrast, transcript levels of nuclear and mitochondrial genes encoding subunits of the mitochondrial electron transport chain are increased or not affected in these mutants. Genomic Southern blot analysis revealed that the DNA amounts of mitochondrial genes are not enhanced in the ispD and ispE albino mutants. These results support the notion that the functional state of chloroplasts may affect the expression of nuclear and mitochondrial genes. The up-regulation of mitochondrial genes in the albino mutants is not caused by changes of mitochondrial DNA copy number in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.org/dc/terms/identifier"doi:10.1007/s11103-008-9297-5"xsd:string
http://purl.uniprot.org/citations/18236010http://purl.org/dc/terms/identifier"doi:10.1007/s11103-008-9297-5"xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/author"Hsieh M.H."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/author"Hsieh M.H."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/author"Chang C.Y."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/author"Chang C.Y."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/author"Chen J.J."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/author"Chen J.J."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/author"Hsu S.J."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/author"Hsu S.J."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/name"Plant Mol. Biol."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/name"Plant Mol. Biol."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/pages"663-673"xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/pages"663-673"xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/title"Chloroplast localization of methylerythritol 4-phosphate pathway enzymes and regulation of mitochondrial genes in ispD and ispE albino mutants in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/title"Chloroplast localization of methylerythritol 4-phosphate pathway enzymes and regulation of mitochondrial genes in ispD and ispE albino mutants in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/volume"66"xsd:string
http://purl.uniprot.org/citations/18236010http://purl.uniprot.org/core/volume"66"xsd:string
http://purl.uniprot.org/citations/18236010http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/18236010
http://purl.uniprot.org/citations/18236010http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/18236010