| http://purl.uniprot.org/citations/18278057 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18278057 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18278057 | http://www.w3.org/2000/01/rdf-schema#comment | "Eukaryotic 20S proteasomes are composed of two alpha-rings and two beta-rings, which form an alphabetabetaalpha stacked structure. Here we describe a proteasome-specific chaperone complex, designated Dmp1-Dmp2, in budding yeast. Dmp1-Dmp2 directly bound to the alpha5 subunit to facilitate alpha-ring formation. In Deltadmp1 cells, alpha-rings lacking alpha4 and decreased formation of 20S proteasomes were observed. Dmp1-Dmp2 interacted with proteasome precursors early during proteasome assembly and dissociated from the precursors before the formation of half-proteasomes. Notably, the crystallographic structures of Dmp1 and Dmp2 closely resemble that of PAC3-a mammalian proteasome-assembling chaperone; nonetheless, neither Dmp1 nor Dmp2 showed obvious sequence similarity to PAC3. The structure of the Dmp1-Dmp2-alpha5 complex reveals how this chaperone functions in proteasome assembly and why it dissociates from proteasome precursors before the beta-rings are assembled."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb.1386"xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb.1386"xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Tanaka K."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Tanaka K."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Hayashi H."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Hayashi H."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Kato K."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Kato K."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Kishimoto T."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Kishimoto T."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Okamoto K."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Okamoto K."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Mizushima T."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Mizushima T."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Suzuki A."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Suzuki A."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Yamane T."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Yamane T."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Takagi K."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Takagi K."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Hirano Y."xsd:string |
| http://purl.uniprot.org/citations/18278057 | http://purl.uniprot.org/core/author | "Hirano Y."xsd:string |