| http://purl.uniprot.org/citations/18292493 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18292493 | http://www.w3.org/2000/01/rdf-schema#comment | "The cytokine IL-27 is important for restricting inflammation in response to a wide variety of immune challenges. In this study, we demonstrate that IL-27 induces expression of the anti-inflammatory cytokine IL-10 by CD4+ and CD8+ T cells. IL-27 relied upon the Th1 transcription factor STAT1 to induce IL-10+IFN-gamma+FoxP3-Th1 cells, which were recently shown to be key negative regulators during certain infections. Il27ra-/-mice generated fewer IL-10+ T cells during both Listeria monocytogenes infection and experimental autoimmune encephalomyelitis. The data presented here indicate a novel mechanism for the induction of IL-10 expression by T cells and provide a mechanistic basis for the suppressive effects of IL-27."xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.180.5.2752"xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/author | "Batten M."xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/author | "Walter M.J."xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/author | "Ghilardi N."xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/author | "de Sauvage F.J."xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/author | "Kljavin N.M."xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/pages | "2752-2756"xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/title | "Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells."xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://purl.uniprot.org/core/volume | "180"xsd:string |
| http://purl.uniprot.org/citations/18292493 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18292493 |
| http://purl.uniprot.org/citations/18292493 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18292493 |
| http://purl.uniprot.org/uniprot/#_Q3UZN3-mappedCitation-18292493 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18292493 |
| http://purl.uniprot.org/uniprot/#_O70394-mappedCitation-18292493 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18292493 |
| http://purl.uniprot.org/uniprot/#_Q8K3I6-mappedCitation-18292493 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18292493 |
| http://purl.uniprot.org/uniprot/O70394 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/18292493 |
| http://purl.uniprot.org/uniprot/Q3UZN3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/18292493 |
| http://purl.uniprot.org/uniprot/Q8K3I6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/18292493 |