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http://purl.uniprot.org/citations/18303585 | http://www.w3.org/2000/01/rdf-schema#comment | "In an earlier study, we showed increases in serotonin 2C receptor (5-HT2CR) pre-mRNA editing in prefrontal cortex that were specific to suicide victims irrespective of associated psychiatric diagnoses. Here we demonstrate that the ratio between the two 5-HT2CR splice variants is increased in people who committed suicide, but does not vary among the diagnostic groups. This provides further evidence for suicide-specific neurobiology and suggests that, as it was previously shown in vitro, 5-HT2CR editing modulates its splicing in human brain. The association analysis indicates, however, that the efficiency of 5-HT2CR editing is an imperfect predictor of the splicing outcome, and that splice site selection is only partially controlled by the level of editing in vivo."xsd:string |
http://purl.uniprot.org/citations/18303585 | http://purl.org/dc/terms/identifier | "doi:10.1097/wnr.0b013e3282f556d2"xsd:string |
http://purl.uniprot.org/citations/18303585 | http://purl.uniprot.org/core/author | "Dracheva S."xsd:string |
http://purl.uniprot.org/citations/18303585 | http://purl.uniprot.org/core/author | "Haroutunian V."xsd:string |
http://purl.uniprot.org/citations/18303585 | http://purl.uniprot.org/core/author | "Chin B."xsd:string |
http://purl.uniprot.org/citations/18303585 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18303585 | http://purl.uniprot.org/core/name | "Neuroreport"xsd:string |
http://purl.uniprot.org/citations/18303585 | http://purl.uniprot.org/core/pages | "379-382"xsd:string |
http://purl.uniprot.org/citations/18303585 | http://purl.uniprot.org/core/title | "Altered serotonin 2C receptor RNA splicing in suicide: association with editing."xsd:string |
http://purl.uniprot.org/citations/18303585 | http://purl.uniprot.org/core/volume | "19"xsd:string |
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