| http://purl.uniprot.org/citations/18304494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18304494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18304494 | http://www.w3.org/2000/01/rdf-schema#comment | "Lumbar-disc degeneration (LDD) is a polygenic disease. Susceptibility genes reported so far are mainly extracellular matrix proteins. D14 allele of asporin (ASPN) is associated with osteoarthritis (OA). Candidate-gene association studies showed that the D14 allele is also significantly associated with LDD in Chinese and Japanese individuals. Meta-analysis showed that individuals harboring a D14 allele had higher risk with a summary odds ratio of 1.70 (p = 0.000013). ASPN expression in vertebral discs increased with age and degeneration. Our results indicate ASPN is a LDD gene in Asians, and common risk factors may be considered for OA and LDD."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ajhg.2007.12.017"xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ajhg.2007.12.017"xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Kawaguchi Y."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Kawaguchi Y."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Chiba K."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Chiba K."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Leong J.C."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Leong J.C."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Hirose Y."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Hirose Y."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Yip S.P."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Yip S.P."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Alini M."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Alini M."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Chan D."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Chan D."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Cheah K.S."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Cheah K.S."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Cheung K.M."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Cheung K.M."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Grad S."xsd:string |
| http://purl.uniprot.org/citations/18304494 | http://purl.uniprot.org/core/author | "Grad S."xsd:string |