| http://purl.uniprot.org/citations/18313658 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18313658 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18313658 | http://www.w3.org/2000/01/rdf-schema#comment | "The generation of a required series of localized Ca(2+) transients during cytokinesis in zebrafish embryos suggests that Ca(2+) plays a necessary role in regulating this process. Here, we report that cortical actin remodeling, characterized by the reorganization of the contractile band and the formation during furrow deepening of pericleavage F-actin enrichments (PAEs), requires a localized increase in intracellular Ca(2+), which is released from IP(3)-sensitive stores. We demonstrate that VAMP-2 vesicle fusion at the deepening furrow also requires Ca(2+) released via IP(3) receptors, as well as the presence of PAEs and the action of calpains. Finally, by expressing a dominant-negative form of the kinesin-like protein, kif23, we demonstrate that its recruitment to the furrow region is required for VAMP-2 vesicle transport; and via FRAP analysis, that kif23 localization is also Ca(2+)-dependent. Collectively, our data demonstrate that a localized increase in intracellular Ca(2+) is involved in regulating several key events during furrow deepening and subsequent apposition."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ydbio.2008.01.027"xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/author | "Miller A.L."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/author | "Miller A.L."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/author | "Chan C.M."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/author | "Chan C.M."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/author | "Webb S.E."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/author | "Webb S.E."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/author | "Li W.M."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/author | "Li W.M."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/name | "Dev. Biol."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/name | "Dev Biol"xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/pages | "228-248"xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/pages | "228-248"xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/title | "Multiple roles of the furrow deepening Ca2+ transient during cytokinesis in zebrafish embryos."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/title | "Multiple roles of the furrow deepening Ca2+ transient during cytokinesis in zebrafish embryos."xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/volume | "316"xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://purl.uniprot.org/core/volume | "316"xsd:string |
| http://purl.uniprot.org/citations/18313658 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18313658 |
| http://purl.uniprot.org/citations/18313658 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18313658 |
| http://purl.uniprot.org/citations/18313658 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18313658 |