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| http://purl.uniprot.org/citations/18316586 | http://www.w3.org/2000/01/rdf-schema#comment | "CDC25A is a critical regulator of cell cycle progression and checkpoint response. Overexpression of this cyclin-dependent kinase phosphatase occurs often in human cancers. Our recent genetic studies in the mouse indicate that restricting CDC25A can limit tumorigenesis induced by the HER2/neu-RAS oncogenic pathway without compromising normal cell division or viability. These findings offer a sound foundation to justify development of CDC25A inhibitors for antitumor therapy."xsd:string |
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| http://purl.uniprot.org/citations/18316586 | http://purl.uniprot.org/core/author | "Ray D."xsd:string |
| http://purl.uniprot.org/citations/18316586 | http://purl.uniprot.org/core/author | "Kiyokawa H."xsd:string |
| http://purl.uniprot.org/citations/18316586 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18316586 | http://purl.uniprot.org/core/name | "Cancer Res"xsd:string |
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| http://purl.uniprot.org/citations/18316586 | http://purl.uniprot.org/core/title | "CDC25A phosphatase: a rate-limiting oncogene that determines genomic stability."xsd:string |
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