RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/1832336http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1832336http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1832336http://www.w3.org/2000/01/rdf-schema#comment"SWI4 of budding yeast codes for a component of a transcription factor (cell cycle box factor, or CCBF) necessary for G1-specific expression of HO. We show that SWI4 is essential for haploid cell viability at high temperature and in a/alpha cells at all temperatures: SWI4-deficient cells arrest as large unbudded cells. Eight high copy number plasmids were identified that allow swi4-strains to grow under nonpermissive conditions. Two carry G1 cyclin genes, CLN1 and CLN2; another carries HCS26, coding for a putative cyclin, a/alpha swi4-mutants exhibit 3-to 20-fold reductions in the levels of CLN1, CLN2, and HCS26 transcripts. The requirement of SWI4 for transcription appears to be direct: each gene contains sites similar to the CCBF-binding site; CCBF binds to the upstream region of HCS26. We propose that SWI4 participates in a positive feedback loop by which CLN1, CLN2, and possibly HCS26 promote their own transcription in G1."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.org/dc/terms/identifier"doi:10.1016/0092-8674(91)90445-5"xsd:string
http://purl.uniprot.org/citations/1832336http://purl.org/dc/terms/identifier"doi:10.1016/0092-8674(91)90445-5"xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/author"Herskowitz I."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/author"Herskowitz I."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/author"Andrews B.J."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/author"Andrews B.J."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/author"Ogas J."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/author"Ogas J."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/pages"1015-1026"xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/pages"1015-1026"xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/title"Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/title"Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription."xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/volume"66"xsd:string
http://purl.uniprot.org/citations/1832336http://purl.uniprot.org/core/volume"66"xsd:string
http://purl.uniprot.org/citations/1832336http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1832336
http://purl.uniprot.org/citations/1832336http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1832336
http://purl.uniprot.org/citations/1832336http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1832336
http://purl.uniprot.org/citations/1832336http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1832336