| http://purl.uniprot.org/citations/18344992 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18344992 | http://www.w3.org/2000/01/rdf-schema#comment | "We report here that amyotrophic lateral sclerosis-linked superoxide dismutase 1 (SOD1) mutants with different biochemical characteristics disrupted the blood-spinal cord barrier in mice by reducing the levels of the tight junction proteins ZO-1, occludin and claudin-5 between endothelial cells. This resulted in microhemorrhages with release of neurotoxic hemoglobin-derived products, reductions in microcirculation and hypoperfusion. SOD1 mutant-mediated endothelial damage accumulated before motor neuron degeneration and the neurovascular inflammatory response occurred, indicating that it was a central contributor to disease initiation."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn2073"xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Zlokovic B.V."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Ali Z."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Zhong Z."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Deane R."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Cleveland D.W."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Sagare A."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "O'Banion M.K."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Parisi M."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Stojanovic K."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Boillee S."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/author | "Shapovalov Y."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/name | "Nat Neurosci"xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/pages | "420-422"xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/title | "ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration."xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/18344992 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18344992 |
| http://purl.uniprot.org/citations/18344992 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18344992 |
| http://purl.uniprot.org/uniprot/#_A0A0U1RPB2-mappedCitation-18344992 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18344992 |
| http://purl.uniprot.org/uniprot/#_E0CZ73-mappedCitation-18344992 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18344992 |
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| http://purl.uniprot.org/uniprot/#_A0A0U1RPW2-mappedCitation-18344992 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18344992 |