| http://purl.uniprot.org/citations/18372357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18372357 | http://www.w3.org/2000/01/rdf-schema#comment | "The objective of this study was to determine risk factors predicting seizures and damage caused by seizures in a multi-ethnic systemic lupus erythematosus cohort (PROFILE) that includes systemic lupus erythematosus patients (n = 1295) from five different US institutions. Only patients with seizures after systemic lupus erythematosus diagnosis (incident) were included in the analyses of clinical seizures (80/1295, 6.2%), but all patients (prevalent and incident) were included in the analyses of damage caused by seizures (51/1295, 3.9%). We examined socioeconomic-demographic, clinical, and genetic variables predictive of clinical seizures and damage from seizures by Cox proportional hazard ratios (HR) and 95% confidence intervals (CI). Independent predictors of a shorter time to the occurrence of clinical seizures were younger age (HR = 1.0; 95% CI 0.9-1.0), having Hispanic-Texan ethnicity (HR = 2.7; 95% CI 1.3-5.7) or African-American ethnicity (HR = 1.8; 95% CI 1.0-3.1), and the previous occurrence of a cerebrovascular accident (HR = 3.3; 95% CI 1.6-7.1) or an episode of psychosis (HR = 2.4; 95% CI 1.1-5.0), whereas the previous occurrence of photosensitivity (HR = 0.5; 95% CI 0.3-0.9) was the only independent predictor of a longer time to the occurrence of clinical seizures. Independent predictors of a shorter time to the occurrence of damage caused by seizures were younger age (HR = 1.0; 95% CI 0.9-1.0), male gender (HR = 2.4; 95% CI 1.1-5.4), and the occurrence of a previous cerebrovascular accident (HR = 2.7; 95% CI 1.0-7.0) or an episode of psychosis (HR = 4.7; 95% CI 2.3-9.9). No allele from the candidate genes examined (HLA-DRB1, HLA-DQB1, FCGR2A, FCGR3A, or FCG3B) predicted clinical seizures or damage caused by seizures."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.org/dc/terms/identifier | "doi:10.1177/0961203307086639"xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/author | "Kimberly R.P."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/author | "Reveille J.D."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/author | "Edberg J.C."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/author | "Ramsey-Goldman R."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/author | "Petri M."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/author | "Alarcon G.S."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/author | "Vila L.M."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/author | "McGwin G."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/name | "Lupus"xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/pages | "177-184"xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/title | "Time to seizure occurrence and damage in PROFILE, a multi-ethnic systemic lupus erythematosus cohort."xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/18372357 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18372357 |
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