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| http://purl.uniprot.org/citations/18381073 | http://www.w3.org/2000/01/rdf-schema#comment | "This study presents gene expression, protein expression, and in situ immunohistochemical evidence that osteoclasts express high levels of osteoactivin (OA), which had previously been reported to be an osteoblast-specific protein in bone. OA expression in osteoclasts was up-regulated upon receptor activator of NFkappaB ligand-induced differentiation. Suppression of functional activity of OA with neutralizing antibody reduced cell size, number of nuclei, fusion, and bone resorption activity of osteoclasts. OA was co-immunoprecipitated with integrin beta3 and beta1, indicating that OA co-localizes with integrin beta3 and/or beta1 in a hetero-polymeric complex in osteoclasts. These findings indicate that OA is a novel osteoclastic protein and plays a role in osteoclast differentiation and/or activity."xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2008.03.030"xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/author | "Mohan S."xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/author | "Lau K.H."xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/author | "Wergedal J.E."xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/author | "Sheng M.H."xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/pages | "1451-1458"xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/title | "Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity."xsd:string |
| http://purl.uniprot.org/citations/18381073 | http://purl.uniprot.org/core/volume | "582"xsd:string |
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