| http://purl.uniprot.org/citations/18381891 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18381891 | http://www.w3.org/2000/01/rdf-schema#comment | "A combination of crystallography, biochemistry, and gene expression analysis identifies the coactivator subcomplex Med8C/18/20 as a functionally distinct submodule of the Mediator head module. Med8C forms a conserved alpha-helix that tethers Med18/20 to the Mediator. Deletion of Med8C in vivo results in dissociation of Med18/20 from Mediator and in loss of transcription activity of extracts. Deletion of med8C, med18, or med20 causes similar changes in the yeast transcriptome, establishing Med8C/18/20 as a predominantly positive, gene-specific submodule required for low transcription levels of nonactivated genes, including conjugation genes. The presented structure-based system perturbation is superior to gene deletion analysis of gene regulation."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.465108"xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "Feldmann H."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "Cramer P."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "Strasser K."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "Hahn S."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "Lariviere L."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "Holstege F.C."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "Seizl M."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "van de Pasch L."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "van Wageningen S."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/author | "Rother S."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/name | "Genes Dev"xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/pages | "872-877"xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/title | "Structure-system correlation identifies a gene regulatory Mediator submodule."xsd:string |
| http://purl.uniprot.org/citations/18381891 | http://purl.uniprot.org/core/volume | "22"xsd:string |
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| http://purl.uniprot.org/uniprot/#_O14198-mappedCitation-18381891 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18381891 |